On a switched full duplex ethernet network the card will under normal conditions just send the frames. There cannot be any collisions because of the full duplex point to point nature of the links.
On an old fassioned CSMA/CD ethernet collision domain the sender can only send if it detects the medium is free. There is still some chance of a collision because two devices could try and transmit at the same time (or at least close enough to the same time that it has to be treated as such). In that cases the devices will back-off for a random time and then try again.
If a switch receives multiple packets destined for a given outgoing port then it will queue them in internal buffers. If the packets keep coming in too fast then the switches buffers will fill, at this point depending on what extensions are supported the switch may send a notification (known as a "pause frame") back to the previous device in the chain or it may just start dropping packets.
Most of the time congestion avoidence algorithms in higher level protocols like TCP will back off the transmit rate avoiding too much packet loss even in cases where there is no effective way of notifying devices earier in the chain of full buffers.
Other physical layers may have different rules.